Meet gestrinone, a hormone that is not recommended by Anvisa

Gestrinone is a hormone used in the treatment of endometriosis, but its use as an aesthetic implant has become popular. However, this purpose is not recommended by Anvisa, and gynecologist Dr. Glaucia Moralles explains how this hormone works and its side effects.

What is gestrinone and what is it used for?

The specialist explains that “gestrinone is a synthetic steroid hormone belonging to the class of progestogens, which has androgenic, antiestrogenic and antiprogestogenic properties. The hormone also acts on the pituitary gland, inhibiting the release of certain hormones called gonadotropins.”

In Brazil, the use of this hormone “was approved only for the oral treatment of endometriosis”, he informs. But she also lists other functions of gestrinone, such as “treating menorrhagia – which is excessive menstrual bleeding – uterine fibroids and breast pain.”

However, he makes it clear that “because of the side effects, this medication is not being used for these purposes”. She explains that gestrinone is “a steroid hormone with properties similar to androgens (male hormones)” and because of that, it has several masculinizing effects.

Thus, its use must be done with care, because “in addition to the noticeable external effects, such as increased hair, fluid retention, voice deepening, increased clitoral size, acne, alopecia and menstrual disorders, there are also effects that may not be present. be seen early on in use and can be even more devastating, such as worsening cholesterol levels and problems with the cardiovascular system”.

Are there contraindications to use?

The doctor informs that the contraindications of the use of this hormone include “liver failure, kidney failure or severe heart failure”. She also highlights that “pregnant women, lactating women and people who have already had a vascular event – such as hormone-induced thrombosis cannot use – are contraindicated to use”.

types of gestrinone

The specialist shows that the only type of presentation of gestrinone approved by Anvisa is the capsule form to be ingested orally, however, the hormone is being manipulated in other ways. Look:

oral capsule

In addition to being the only form approved by Anvisa, to consume this drug it is necessary to manipulate it, because “there are no ready-made forms in pharmacy currently, so the only alternative would be to manipulate it”. Even though it was used for endometriosis, “its use has been discontinued due to the various existing side effects, mainly androgenic effects”.

“Beauty Chip”

Dr. Moralles explains that “currently, there are other pharmaceutical forms manipulated, such as subcutaneous implants, also called by some ‘beauty chip’, for a possible aesthetic effect, which is to reduce body fat and favor lean mass gain”. However, she reinforces that “it is important to make it clear that, according to Anvisa, the manipulation and commercialization of the substance for use in the form of implant, therapeutic or aesthetic use is not allowed”.

vaginal gel

“Another manipulated presentation would be the gel for vaginal use, used by some doctors to treat symptoms of endometriosis”, explained the doctor.

Thus, it is important to highlight that gestrinone should not be used for aesthetic purposes, being contraindicated due to its various side effects.

Questions about gestrinone

Do you have questions about the use of this hormone? Dr. Glaucia Moralles answers the most common doubts that exist on this topic. Look:

Does using gestrinone prevent pregnancy?

Dr. Glaucia Moralles (GM): No. Gestrinone is not approved for use as a contraceptive.

Does menstruation stop?

GM: Most gestrinone users stop menstruating within the first few months of use.

Can its use cause acne?

GM: Yes. Due to its effect similar to that of male hormones.

Can it be used for aesthetic purposes?

GM: No. To date, there are no studies indicating safety for the aesthetic use of gestrinone.

Is using the “beauty chip” safe?

GM: No. According to the Brazilian Federation of Gynecology and Obstetrics Associations (FEBRASGO) and the Brazilian Society of Endocrinology and Metabology (SBEM), currently the efficacy and safety that justify the use of these implants have not been established.

How long does gestrinone take to work?

GM: The action can start about 2 hours after being administered and remains circulating in the blood for about 27 hours after being ingested. Despite this, when using medication to treat endometriosis, the effects can take weeks or months to appear. Another situation to be observed is that some effects can take many months to disappear and even after its use is stopped, some effects can be permanent, such as an increase in the size of the clitoris.

What is the average price of gestrinone?

GM: The values ​​are quite variable and there is no way to stipulate an average price, as they vary according to the region of the country.

For whom is the use of gestrinone recommended?

GM: Gestrinone is recommended and approved only for use in patients who need treatment for endometriosis.

Now you know the most important information about the action of gestrinone in the body, continue reading to check the reports of people who have already used this hormone.

Experiences and reports from those who have used it

To understand more about the subject, see the selection of videos with reports of people who have had a hormonal implant or a beauty chip:

gestrinone hormonal implant

In this video, Bela shares her negative experience with the implant. She highlights that she has endometriosis and, therefore, the use was indicated for her. Even so, she does not recommend using it for aesthetic reasons.

Gestrinone accompanied by other hormones

Blogger Nah Cardoso also made use of the famous beauty chip. Unlike the first video, the aim was to use the hormone as a contraceptive method. So, see the blogger’s report and find out why she doesn’t recommend using it.

For some people the benefits are worth the side effects.

In this video, Meiri Coracini shares her experience with the beauty chip. The blogger explains that she put it on for hormonal disruption and, despite the benefits being greater than the side effects, the influencer draws attention to the seriousness of these implants and not to use them as a weight loss method.

Therefore, care is needed before starting to use gestrinone. Did you like the article? Also check out the different types of birth control pills for a safer contraceptive method.

The information contained on this page is for informational purposes only. They do not replace the advice and follow-up of doctors, nutritionists, psychologists, physical education professionals and other specialists.