The worst medicines for the liver

He liver It is a vital organ that performs essential functions to keep our body healthy. One of the most crucial is break down toxic substances and remove them from the bodysomething that makes it the main responsible for process and eliminate drugs from our body what we consume

However, the liver has its limits and cannot process everything we eat. When certain drugs are taken in excessive doses or for long periods of time, can cause liver damage. should know the worst medicines for the liver and do not resort to them unless it is strictly necessary.

the worst medicines for the liver

There are various medications that taken in excess, can damage the liver and among the most prominent are:

He paracetamol (also called acetaminophen) is a very popular medication for treat pain or fever. It is metabolized in the liver and in large quantities (greater than the recommended doses) it can produce toxic substances (toxic metabolites) that can damage liver cells.

The non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen or naproxen, are used to reduce fever and inflammation and relieve pain. They can cause liver damage and other gastrointestinal problems.some antibiotics can damage the liver, especially if taken over a long period of time. statinsused for lower cholesterolcan cause liver damage in some patients. anticonvulsants are drugs used to treat epilepsy which in some cases can cause liver damage, especially if taken in high doses.

In any case, it is important to emphasize that you should never stop taking prescription drugs on your own by the doctor, since in your case the benefits they provide may be more important than their possible risks.

It should also be mentioned that people who have previous liver disease They may be at increased risk of liver damage caused by medications.

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Mechanisms by which liver damage occurs

Liver damage caused by medications can occur in a number of ways, including:

direct toxicitythat is, there are drugs that are toxic to liver cells. Some drugs, being metabolized by the livergenerate toxic substances that can damage liver cells. Some medications can interact with other medications They are metabolized in the liver, which may increase the risk of liver damage.

On the other hand, it can also happen that the person is allergic to a drug or its components and the allergic reaction cause inflammation and liver damage.

What liver problems can medicines cause?

Medications can affect the liver in different ways, depending on the type of medication, the dose, and the duration.

Hepatic injury: Prolonged exposure or excessive doses of certain drugs can damage liver cells and affect liver function. This can cause iinflammation of the liver, fibrosis, cirrhosis and, in severe cases, liver failure.Hepatic steatosis: some medicines, by accumulating in the liver, can cause a accumulation of fat in the liver. If left untreated, it can lead to liver inflammation and cirrhosis.Hepatitis (inflammation of the liver). It can occur as a result of an immune reaction of the body to the drug. cholestasis is a decreased bile flow from the liver. May cause liver inflammation and other health problems.

To reduce the risk of this (or any other drug-related unwanted effect) occurring, it is critical not toor exceed the recommended dose and time by the doctor.

In general, liver damage resolves once the medications are stopped. However, in some cases the can be permanent and even endanger life.